Tissue Partial Volume Correction of Perfusion Maps in Dynamic Susceptibility Contrast MRI
André Ahlgren1, Ronnie Wirestam1, Freddy Ståhlberg1,2,3, and Linda Knutsson1
1Department of Medical Radiation Physics, Lund University, Lund, Sweden, 2Department of Diagnostic Radiology, Lund University, Lund, Sweden, 3Lund University Bioimaging Center, Lund University, Lund, Sweden
effects (PVE) can significantly affect parameter estimates in perfusion MRI. In
contrast to arterial spin labeling (ASL), the impact of PVEs in dynamic
susceptibility contrast MRI (DSC-MRI) has not yet been well established. In
this work, we assess and compare partial volume correction (PVC) of DSC-MRI and
ASL data in 20 healthy subjects. PVC reduced the tissue volume dependence of
perfusion estimates in DSC-MRI and ASL. White matter perfusion maps were of
higher quality for DSC-MRI. However, for PVC of DSC-MRI we used several assumptions which need further evaluation.
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