Marco Pizzolato1, Rutger Fick1, Timothé Boutelier2, and Rachid Deriche1
Bolus dispersion phenomena affect the residue function computed via
deconvolution of DSC-MRI data. Indeed the obtained effective residue
function can be expressed as the convolution of the true one with a
Vascular Transport Function (VTF) that characterizes the dispersion.
The state-of-the-art technique CPI+VTF allows to estimate the actual
residue function by assuming a model for the VTF. We propose to
perform deconvolution representing the effective residue function
with Dispersion-Compliant Bases (DCB) without assumptions on the VTF,
and then apply the CPI+VTF on DCB results. We show that DCB improve
robustness to noise and allow to better characterize the VTF.