Priors-guided adaptive outlier cleaning for arterial spin labeling perfusion MRI
1Hangzhou Normal University, Hangzhou, China, People's Republic of, 2Psychiatry and Radiology, University of Pennsylvania, PHILADELPHIA, PA, United States
ASL CBF signal is derived from the difference between successive
labeling and no-labeling images. The low signal-to-noise-ratio and the pairwise subtraction can then
result in outliers, which can significantly degrade CBF quantification quality
in a typical several minutes scan. A priors-guided adaptive outlier cleaning
algorithm was verified in this study. Our results showed that the proposed
method improved both CBF quantification quality and CBF measurement stability.
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