Abstract #1523

Selective Amide- and NOE-CEST- MRI in Prostate at 7T using a Multi-transmit system

Catalina S. Arteaga de Castro¹, Hans J.M. Hoogduin¹, Vitaliy Khlebnikov¹, Peter R. Luijten¹, Dennis W.J. Klomp¹, and Moritz Zaiss²

¹Imaging Division, University Medical Center Utrecht, Utrecht, Netherlands, ²Medical Physics in Radiology, German Cancer Research Center, Heidelberg, Germany

The feasibility of selective NOE- and amide-CEST detection in the prostate at 7T was investigated with a multi-transmit system. Both effects can be acquired simultaneously due to the increased sensitivity and spectral resolution available at 7T. Fitted NOE- and amide-CEST were reproducible within experiments. NOE-CEST was found to be more pronounced than amide-CEST in small and whole prostate ROIs and the peripheral zone showed the lowest amide- and NOE-CEST effects.

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