Abstract #1549

Are susceptibility-weighted imaging and quantitative susceptibility mapping suitable to gain additional information on melanoma metastasis of the brain?

Sina Straub¹, Till Schneider^2,3, Christian H. Ziener³, Heinz-Peter Schlemmer³, Mark E. Ladd¹, Frederik B. Laun¹, and Martin T. Freitag³

¹Department of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany, ²Department of Neuroradiology, University of Heidelberg, Heidelberg, Germany, ³Department of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

The benefit of susceptibility weighted imaging (SWI) and quantitative susceptibility mapping (QSM) for the detection and quantification of bleeding of brain metastases of malignant melanoma is assessed. QSM shows paramagnetic values for hemorrhagic metastases (0.355±0.097 ppm) and less paramagnetic values (0.239±0.123 ppm) for hemorrhagic metastases that have T1w-native hyperintense signal. Moreover, our findings suggest that T1w-native hyperintense melanoma metastases have relatively diamagnetic susceptibility compared to other structures of the brain.

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