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Abstract #1557

Quantitative Susceptibility Mapping Using Adaptive Edge-Preserving Filtering: Comparison with COSMOS in Human Brain

Toru Shirai1, Ryota Sato1, Yo Taniguchi1, Takenori Murase2, Atsushi Kuratani2, Taisei Ueda2, Takashi Tsuneki2, Yoshitaka Bito2, and Hisaaki Ochi1

1Research and Development Group, Hitachi, Ltd., Tokyo, Japan, 2Healthcare Campany, Hitachi, Ltd., Chiba, Japan

We have proposed that a QSM reconstruction method combining an iterative least square minimization and adaptive edge-preserving filtering could generate high-quality susceptibility maps. In this study, maps calculated by the proposed method were compared qualitatively and quantitatively with those calculated by COSMOS (a calculation of susceptibility through multiple-orientation sampling) in healthy volunteers. The results from human brain experiments showed good agreement with COSMOS. The proposed QSM reconstruction of single orientation sampling is useful for generating a high-quality susceptibility map of the human brain.

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