Abstract #1557

Quantitative Susceptibility Mapping Using Adaptive Edge-Preserving Filtering: Comparison with COSMOS in Human Brain

Toru Shirai¹, Ryota Sato¹, Yo Taniguchi¹, Takenori Murase², Atsushi Kuratani², Taisei Ueda², Takashi Tsuneki², Yoshitaka Bito², and Hisaaki Ochi¹

¹Research and Development Group, Hitachi, Ltd., Tokyo, Japan, ²Healthcare Campany, Hitachi, Ltd., Chiba, Japan

We have proposed that a QSM reconstruction method combining an iterative least square minimization and adaptive edge-preserving filtering could generate high-quality susceptibility maps. In this study, maps calculated by the proposed method were compared qualitatively and quantitatively with those calculated by COSMOS (a calculation of susceptibility through multiple-orientation sampling) in healthy volunteers. The results from human brain experiments showed good agreement with COSMOS. The proposed QSM reconstruction of single orientation sampling is useful for generating a high-quality susceptibility map of the human brain.

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