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Abstract #1558

QSM at 3T: Comparison of Acquisition Methodologies

M Louis Lauzon1,2,3, Cheryl Rae McCreary1,2,3, D Adam McLean3,4, Marina Salluzzi3,4, and Richard Frayne1,2,3

1Radiology and Clinical Neurosciences, University of Calgary, Calgary, AB, Canada, 2Hotchkiss Brain Institute, Calgary, AB, Canada, 3Seaman Family MR Research Centre, Calgary, AB, Canada, 4Calgary Image Processing and Analysis Centre, Calgary, AB, Canada

We scanned 4 volunteers 3 times each using 8 different QSM variants (unipolar/bipolar readout gradient, accelerated or not, with/without gradient warp-correction), and compared the susceptibility (average and standard deviation) in five deep gray matter tissues using linear mixed effects modeling. Gradient-warp correction was found to decrease the susceptibility estimates by 3-5%, whereas there was no statistical difference in the estimates due to readout polarity or acceleration factor.

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