Abstract #1558

QSM at 3T: Comparison of Acquisition Methodologies

M Louis Lauzon^1,2,3, Cheryl Rae McCreary^1,2,3, D Adam McLean^3,4, Marina Salluzzi^3,4, and Richard Frayne^1,2,3

¹Radiology and Clinical Neurosciences, University of Calgary, Calgary, AB, Canada, ²Hotchkiss Brain Institute, Calgary, AB, Canada, ³Seaman Family MR Research Centre, Calgary, AB, Canada, ⁴Calgary Image Processing and Analysis Centre, Calgary, AB, Canada

We scanned 4 volunteers 3 times each using 8 different QSM variants (unipolar/bipolar readout gradient, accelerated or not, with/without gradient warp-correction), and compared the susceptibility (average and standard deviation) in five deep gray matter tissues using linear mixed effects modeling. Gradient-warp correction was found to decrease the susceptibility estimates by 3-5%, whereas there was no statistical difference in the estimates due to readout polarity or acceleration factor.

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