Abstract #1571

Post-mortem reperfusion of the vascular system and examination in MRI: Temperature-dependent characterisation of perfusates and contrast simulations

Bridgette Webb¹, Thomas Widek¹, Bernhard Neumayer¹, Rudolf Stollberger², and Thorsten Schwark^1,3

¹Ludwig Boltzmann Institute for Clinical Forensic Imaging, Graz, Austria, ²Institute of Medical Engineering, Graz University of Technology, Graz, Austria, ³Institute of Legal Medicine, Medical University of Graz, Graz, Austria

MRI evaluation of a post-mortem reperfused cardiovascular system requires a complete filling of vessels, acceptable contrast/image quality and consideration of temperature influences. Assessment of the temperature dependence of viscosity, T1 and T2 of candidate perfusates (n=10) found 3 to be suitable for application in post-mortem MR angiography. Bloch equation simulations were applied to investigate contrast between these liquids and post-mortem myocardium at 1, 8.5, 16 and 23°C. For a FLASH sequence, optimal flip angles were affected by temperature variation and a decrease in contrast (max. 6-12%) was observed when flip angles optimised for one of the other temperatures were applied.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.