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Abstract #1570

dcQSM: Quantitative Susceptibility Mapping by Directly Fitting Complex Images

Zhe Liu1, Pascal Spincemaille2, and Yi Wang1,2

1Biomedical Engineering, Cornell University, Ithaca, NY, United States, 2Radiology, Weill Cornell Medical College, New York, NY, United States

The quality of Quantitative Susceptibility Mapping (QSM) depends critically on a correct estimation of total magnetic field, which may sometimes be degraded by phase unwrapping failure. We propose to bypass the traditional field estimation and phase unwrapping steps and estimate both background field and local susceptibility distribution directly from complex GRE images, which is referred to as dcQSM. Since no field is explicitly existent in our method, dcQSM eliminates phase unwrapping errors in tradition methods.

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