Abstract #1573

Black-Blood T2* Mapping with Delay Alternating with Nutation for Tailored Excitation

Shi Su¹, Yanan Ren¹, Caiyun Shi¹, Xiaoyong Zhang^1,2, Hairong Zheng¹, Xin Liu¹, and Guoxi Xie¹

¹Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, People's Republic of, ²Centers for Biomedical Engineering, College of Information Science and Technology, University of Science and Technology of China, Hefei, China, People's Republic of

T2* mapping provides a means to quantitatively estimate the iron load of tissue, which is closely related to numerous diseases, such as thalassemia, hereditary hemochromatosis and sickle cell disease. However, blood signal would induce artifacts which lead to T2* estimation inaccurate. To address this issue, a novel black-blood T2* mapping technique utilizing Delay Alternating with Nutation for Tailored Excitation (DANTE) preparation module followed by multi-echo gradient echo (GRE) readout (DANTE-GRE) was developed to obtain blood suppressed T2* maps. The proposed method is shown to acquire more accurate T2* maps due to its high SNR and effective blood signal suppression.

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