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Abstract #1573

Black-Blood T2* Mapping with Delay Alternating with Nutation for Tailored Excitation

Shi Su1, Yanan Ren1, Caiyun Shi1, Xiaoyong Zhang1,2, Hairong Zheng1, Xin Liu1, and Guoxi Xie1

1Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, People's Republic of, 2Centers for Biomedical Engineering, College of Information Science and Technology, University of Science and Technology of China, Hefei, China, People's Republic of

T2* mapping provides a means to quantitatively estimate the iron load of tissue, which is closely related to numerous diseases, such as thalassemia, hereditary hemochromatosis and sickle cell disease. However, blood signal would induce artifacts which lead to T2* estimation inaccurate. To address this issue, a novel black-blood T2* mapping technique utilizing Delay Alternating with Nutation for Tailored Excitation (DANTE) preparation module followed by multi-echo gradient echo (GRE) readout (DANTE-GRE) was developed to obtain blood suppressed T2* maps. The proposed method is shown to acquire more accurate T2* maps due to its high SNR and effective blood signal suppression.

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