Abstract #1600

MR imaging of saline flooded lung – A feasibility study in a large animal model

Frank Wolfram¹, Thomas Lesser¹, Harald Schubert², Joachim Böttcher³, Jürgen R Reichenbach⁴, and Daniel Güllmar⁴

¹Department of Thoracic and Vascular Surgery, SRH Wald-Klinikum Gera, Teaching Hospital of Friedrich Schiller University of Jena, Gera, Germany, ²Institute of Laboratory Animal Sciences and Welfare, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany, ³Institute of Diagnostic and Interventional Radiology, SRH Wald-Klinikum Gera, Teaching Hospital of Friedrich Schiller University of Jena, Gera, Germany, ⁴Medical Physics Group / IDIR, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany

MR imaging of ventilated lung is a challenging task. The low proton density with extremely short T2* and local field inhomogeneities on tissue-air interfaces are sub-optimal for MRI. Unilateral lung flooding replaces air content of one lung wing with saline. This experimental method enables sonographic guidance as well as therapeutic ultrasound ablation. The untoward properties of lung might change to ideal conditions with a homogen and high proton density after flooding. The aim of the study was to investigate the feasibility of in-vivo unilateral lung flooding in MR environment and to evaluate the MR imaging capabilities of flooded lung in a large animal model.

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