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Abstract #1602

Optimized four channel phased array coil for mice lung imaging at 11.7 T

Marta Tibiletti1, Dominik Berthel2, Michael Neumaier3, Dorothee Schüler2, Detlef Stiller3, and Volker Rasche1,4

1Core Facility Small Animal MRI, Ulm University, Ulm, Germany, 2Rapid Biomedical GmbH, Rimpar, Germany, 3Target Discovery Research, In-vivo imaging laboratory, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany, 4Department of Internal Medicine II, Ulm University, Ulm, Germany

Lung imaging with MRI is challenging, due to the low proton density in the tissue, short T2* values due to multiple air-tissue interfaces, and respiratory and cardiac motion. A major step for providing sufficient signal to noise ratio (SNR) is the availability of dedicated coils optimized for the specific application. In this work, we present a 4-channel mouse phased-array coil optimized for the thoracic anatomy of mice. Depending on the field-of-view an average two- to threefold gain in SNR was observed in direct comparison to a conventional transmitt/receive quadrature volume coil at 11.7 T.

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