Abstract #1602

Optimized four channel phased array coil for mice lung imaging at 11.7 T

Marta Tibiletti¹, Dominik Berthel², Michael Neumaier³, Dorothee Schüler², Detlef Stiller³, and Volker Rasche^1,4

¹Core Facility Small Animal MRI, Ulm University, Ulm, Germany, ²Rapid Biomedical GmbH, Rimpar, Germany, ³Target Discovery Research, In-vivo imaging laboratory, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany, ⁴Department of Internal Medicine II, Ulm University, Ulm, Germany

Lung imaging with MRI is challenging, due to the low proton density in the tissue, short T2* values due to multiple air-tissue interfaces, and respiratory and cardiac motion. A major step for providing sufficient signal to noise ratio (SNR) is the availability of dedicated coils optimized for the specific application. In this work, we present a 4-channel mouse phased-array coil optimized for the thoracic anatomy of mice. Depending on the field-of-view an average two- to threefold gain in SNR was observed in direct comparison to a conventional transmitt/receive quadrature volume coil at 11.7 T.

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