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Abstract #1640

MR angiography of congenital portosystemic shunts in mice

Hongxia Lei1,2, Ana Francisca Soares3, and Rolf Gruetter3,4

1Animal Imaging and Technology CIBM-AIT, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2University of Geneva, Geneva, Switzerland, 3Laboratory of functional and metabolic imaging LIFMET, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 4University of Lausanne, Lausanne, Switzerland

Abnormal vascular connections within the liver, such as congenital portosystemic shunts occur sporadically in widely used strain of laboratory mice, i.e. the C57BL/6J strain. We showed that with the respiration gating, MR angiography yields vascular structures of mouse liver with excellent quality and thus allowing diagnosing such abnormality non-invasively.

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