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Abstract #1641

In vivo 31P 3D MRSI of the hepatobiliary system with improved coverage due to the 8 channel receive array at 3T enables prospective assessment of phosphatidylcholine in the gallbladder.

Marek Chmelik1,2, Martin Gajdošík1,2, Emina Halilbasic3, Ladislav Valkovič1,4, Wolfgang Bogner1, Stephan Gruber1, Michael Trauner3, Siegfried Trattnig1,2, and Martin Krššák1,2,3

1High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 2Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, 3Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria, 4OCMR, RDM Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom

The purpose of this study was to acquire 31P-3D-MRSI data with extended coverage of the hepatobiliary system using a 8-channel receive array at 3T. This protocol enables prospective phosphatidylcholine (PtdC) assessment in the gallbladder. As the bile amount in the gallbladder changes according to dietary condition, the protocol was tested pre-/post-meal. After overnight fasting all volunteers had gallbladder filled with the bile visible in both 31P-MRSI data as strong PtdC signal at 2ppm and in T2 weighted images as hyperintense region. A reduced PtdC signal and volume of the gallbladder were visible after digestion of the high fat meal.

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