Marek Chmelik1,2, Martin Gajdošík1,2, Emina Halilbasic3, Ladislav Valkovič1,4, Wolfgang Bogner1, Stephan Gruber1, Michael Trauner3, Siegfried Trattnig1,2, and Martin Krššák1,2,3
1High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 2Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, 3Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria, 4OCMR, RDM Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom
The purpose of this study was to acquire 31P-3D-MRSI
data with extended coverage of the hepatobiliary system using a 8-channel
receive array at 3T. This protocol enables prospective phosphatidylcholine (PtdC)
assessment in the gallbladder. As the bile amount in the gallbladder changes according
to dietary condition, the protocol was tested pre-/post-meal. After overnight
fasting all volunteers had gallbladder filled with the bile visible in both 31P-MRSI
data as strong PtdC signal at 2ppm and in T2 weighted images as hyperintense
region. A reduced PtdC signal and volume of the gallbladder were visible after digestion
of the high fat meal.
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