Abstract #1644

Multi-Institution Liver Mass Evaluation at 1.5 and 3 T Using Free breathing, Through-time Spiral GRAPPA and Quantitative Perfusion

Shivani Pahwa¹, Hao Liu², Yong Chen³, Sara Dastmalchian¹, Ziang Lu¹, Chaitra Badve⁴, Alice Yu¹, Joshua Batesole⁴, Hamid Chalian⁴, Katherine Wright¹, Shengxiang Rao⁵, Caixia Fu⁶, Ignacio Vallines⁷, Dean Nakamoto⁸, Mark Griswold⁹, Nicole Seiberlich¹⁰, Zeng Mengsu¹¹, and Vikas Gulani¹²

¹Radiology, Case Western Reserve University, Cleveland, OH, United States, ²Zhongshan Hospital, Fudan University, Shanghai, China, People's Republic of, ³Case Western Reserve University, Cleveland, OH, United States, ⁴Radiology, University Hospitals, Cleveland, OH, United States, ⁵Zhongshan Hospital< Fudan University, Shanghai, China, People's Republic of, ⁶Siemens, Shanghai, China, People's Republic of, ⁷Siemens Healthcare, Shanghai, China, People's Republic of, ⁸Radiology, Case Western Reserve University and University Hospitals, Cleveland, OH, United States, ⁹Radiology and Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ¹⁰Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ¹¹Radiology, Zhongshan Hospital, Fudan University, Shanghai, China, People's Republic of, ¹²Radiology, University Hospitals Case Medical Center, Cleveland, OH, United States

Breath holds and lack of a quantitative dimension are the two major challenges in liver MR imaging. Free breathing, perfusion sequences created in academic institutions in the developed world have not been tested in busy and overloaded radiology practices worldwide. We evaluated free-breathing, 3D Through-time Spiral GRAPPA perfusion technique at two different field strengths in the US and China. We found that the perfusion parameters obtained for two most common hepatic lesions ie hepatocellular carcinoma and metastases were remarkably consistent across sites, though statistically different according to pathology.

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