Abstract #1645

Rapid Liver Strain Assessment in a Single Breath-hold using MR Tagging and FastHARP

Nader S. Metwalli^1,2, Ronald Ouwerkerk¹, Ahmed M. Gharib¹, and Khaled Z. Abd-Elmoniem¹

¹Biomedical and Metabolic Imaging Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States, ²Biomedical Engineering Department, Cairo University, Giza, Egypt

Liver fibrosis occurs as a result of long standing chronic liver disease of various etiologies. Reversibility of liver fibrosis has generated considerable attention lately. Early detection of increased liver stiffness would potentially guide towards more effective treatments. Our accelerated acquisition of liver tagging MRI to assess liver mechanics allows larger volumetric coverage and a substantially shorter acquisition time (≈ 80% reduction of total acquisition) than conventional tagging whilst delivering comparable results.

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