Abstract #1689

Structural and Functional Brain Alterations in Uremic restless legs syndrome patients: A Voxel-Based Morphometry and Functional Connectivity Study

DUN DING¹, PENG LI², Ji Xin Liu², Xue Ying Ma², and Ming Zhang²

¹XI'AN JIAO TONG UNIVERSITY, XI'AN, China, People's Republic of, ²XI'AN, China, People's Republic of

To investigate the structure and function changes in the brain in uremic RLS patients using a resting-state function magnetic resonance imaging (fMRI) paradigm, we used A voxel-based morphometry(VBM) method and a seed-based method to find the abnormiy in end-stage kidney disease patients. Our results suggest that the characteristics of the connectivity changes may reflect the pathways involved in producing uremic RLS symptoms.

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