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Abstract #1730

Altered structural-functional connectome in unilateral sudden sensorineural hearing loss

Wenliang Fan1 and Haibo Xu1,2

1Department of Radiology, Union Hospital, Tongji Medical College,Huazhong University of Science and Technology, Wuhan, China, People's Republic of, 2Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China, People's Republic of

We used graph theoretical network analysis method to explore the alterations of brain structural–functional connectome in two large samples of unilateral sudden sensorineural hearing loss patients within the acute period. While previous neuroimaging studies have uncovered alterations in several specific brain structural and functional networks in patients with USSHL, little is known about the changes in the relationship between structural and functional brain connectome. And how do functional brain networks emerge from structural brain connectivity in USSHL is still unknown.

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