Abstract #1743

Calibration, validation, and sensitivity analysis of a 3D method for the mapping of brain venous oxygenation

Deng Mao^1,2, Yang Li¹, Peiying Liu¹, Shin-Lei Peng³, and Hanzhang Lu¹

¹Russell H. Morgan Department of Radiology, Johns Hopkins University, Baltimore, MD, United States, ²Graduate School of Biomedical Sciences, Univ of Texas Southwestern Medical Center, Dallas, TX, United States, ³Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan

The present study aimed to further develop and investigate of a non-invasive, efficient and reproducible technique to map brain venous oxygenation in 3D. We first improved the processing pipeline by substracting angiogram to remove arterial content and apply threholdings to eliminate poor fitted and low signal voxels. We then calibrated T2* to oxygenation relationship in vitro using the same technique. In addition, we used hyperoxia challenge to test its sensitivity and combined TRUST MRI method for validation.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.