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Abstract #1756

A more sensitive paradigm for direct MR detection of neuronal currents: simulation results

Ileana Hancu1 and Christopher Hardy1

1GE Global Research Center, Niskayuna, NY, United States

Direct detection of neuronal activity through MRI is an active research area. Typical MRI-based approaches for direct detection of neuronal currents use echo-planar imaging, which offers wide spatial coverage at low temporal resolution (>100ms). In this work, we explore a significantly different paradigm, in which we give up wide spatial coverage, gaining the capability of sampling signals at much higher rates. Our simulation results indicate that the ability to compare entire time curves sampled at a high temporal rate leads to an increase in the sensitivity of detecting neuronal currents by a factor of at least 10.

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