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Abstract #1910

Improvement in Glioma Visualization using Subtraction Maps Derived from Contrast-Enhanced T1- and T2-Weighted MR Images

Mohammed Goryawala1, Bhaswati Roy2, Rakesh K Gupta2, and Andrew A Maudsley1

1Department of Radiology, University of Miami, Miami, FL, United States, 2Department of Radiology, Fortis Memorial Research Institute, Gurgaon, India

Calculated differences between two images of differing T1 or T2 contrasts, or subtraction images, have been presented as a way to improve image contrast for imaging of brain tumors. In this study the performance of subtraction images for differentiation of tumor, edema, and normal appearing white matter (NAWM) is compared to traditionally acquired anatomic MRIs, diffusion tensor imaging (DTI), perfusion weighted imaging (PWI) and MR spectroscopy imaging (MRSI). Results showed a significant increase in contrast for differentiating between enhancing tumor and edematous regions from NAWM using the ΔT1 map and ΔT2 map, respectively, as compared to other parametric maps.

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