Mohammed Goryawala1, Bhaswati Roy2, Rakesh K Gupta2, and Andrew A Maudsley1
1Department of Radiology, University of Miami, Miami, FL, United States, 2Department of Radiology, Fortis Memorial Research Institute, Gurgaon, India
Calculated
differences between two images of differing T1 or T2 contrasts, or subtraction
images, have been presented as a way to improve image contrast for imaging of
brain tumors. In this study the performance of subtraction images for differentiation
of tumor, edema, and normal appearing white matter (NAWM) is compared to traditionally
acquired anatomic MRIs, diffusion tensor imaging (DTI), perfusion weighted
imaging (PWI) and MR spectroscopy imaging (MRSI). Results showed a significant
increase in contrast for differentiating between enhancing tumor and edematous
regions from NAWM using the ΔT1 map and ΔT2 map, respectively, as compared to
other parametric maps.
