Abstract #1943

MR elastography of intracranial tumors: Initial experience with high-resolution imaging and nonlinear inversion

Curtis L Johnson¹, Emily S Matijevich^1,2, Emily D Cullum^1,2, Matthew DJ McGarry³, Keith D Paulsen³, Bradley P Sutton^1,4, Tracey M Wszalek^1,2, and William C Olivero^1,2

¹Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, United States, ²Carle Neuroscience Institute, Carle Foundation Hospital, Urbana, IL, United States, ³Thayer School of Engineering, Dartmouth College, Hanover, NH, United States, ⁴Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States

MR elastography has emerged as an important tool for presurgical evaluation of intracranial tumors. Due to the localized nature of the lesion properties of interest, there is a need for high-resolution MRE methods for characterizing tumors. Here we present our initial experience with MRE of intracranial tumors using a protocol based on high-resolution imaging and nonlinear inversion. We found that glial tumors are soft and have a generally low viscosity, while meningeal tumors are stiff and have a very low viscosity.

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