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Abstract #1952

Impact of Field Strength and Image Resolution on MRE Stiffness Estimation

Eric Barnhill1, Jing Guo2, Florian Dittmann2, Sebastian Hirsch2, Michael Perrins3, Lucy Hiscox3, Tim Herrmann4, Johannes Bernarding4, Neil Roberts3, Jürgen Braun1, and Ingolf Sack2

1Institute of Medical Informatics, Charité Universitätsmedizin Berlin, Berlin, Germany, 2Department of Radiology, Charité Universitätsmedizin Berlin, Berlin, Germany, 3Clinical Research Imaging Centre, The University of Edinburgh, Edinburgh, United Kingdom, 4Institute for Biometrics and Medical Informatics, Otto von Guericke University Magdeburg, Magdeburg, Germany

We investigated the impact of field strength and image resolution on brain MRE stiffness results. A cohort of 18 healthy volunteer subjects was scanned at 1.5T (2mm isotropic voxels), 3T (2mm) and 7T (1mm), with a fourth set downsampling the 7T to 2mm. Means were 1634 Pa (+/-613) for 1.5T, 1743 Pa (+/-811) for 3T, 1786 (+/-634) Pa for 7T 2mm, and 927 (+/-364) Pa for 7T 1mm. In the paired sign-rank tests, there were no significant effects for field strength. Examination of histograms of example slices suggests that a different distribution of features is being captured at the higher resolution.

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