Abstract #1953

Investigation Of The Relationship Between Feature Detail And Stiffness Estimate In Magnetic Resonance Elastography (MRE) Elastograms

Eric Barnhill¹, Florian Dittmann², Sebastian Hirsch², Jing Guo², Jürgen Braun¹, and Ingolf Sack²

¹Institute of Medical Informatics, Charité Universitätsmedizin Berlin, Berlin, Germany, ²Department of Radiology, Charité Universitätsmedizin Berlin, Berlin, Germany

Magnetic Resonance Elastography (MRE) stiffness estimates show differentiated results by feature scale. Here progressive denoising was applied to study the relation between image sharpness (as meaured by Reduced Energy Ratio) and image stiffness estimate (as measured by complex shear modulus magnitude |G*|). Progressive complex-wavelet-based denoising appears to reach stable stiffness estimates in phantom and brain acquisitions. Images of maximum sharpness result in lower overall stiffness estimates than the stable global estimate, suggesting that coarse elasticity estimates do not average fine feature results, but measure a different stiffness scale.

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