Abstract #1969

Intravoxel incoherent motion MRI in primary rectal cancer: correlation with histologic prognostic factors

Zhe Han^1,2, Juan Chen², Min Chen², Chen Zhang², and Lizhi Xie³

¹Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China, People's Republic of, ²Department of Radiology, Beijing Hospital, Beijing, China, People's Republic of, ³GE Healthcare, MR Research China, Beijing, China, People's Republic of

In this study we compared the association of intravoxel incoherent motion (IVIM) derived parameters with the histologic grade, N-stage, EGFR expression and K-RAS gene mutation of primary rectal cancer. Significant correlations were found between D values and differentiation grade, D* values and N-stage, f values and N-stage. IVIM derived parameters may be a promising imaging biomarker of tumor aggressiveness and prognosis.

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