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Abstract #1969

Intravoxel incoherent motion MRI in primary rectal cancer: correlation with histologic prognostic factors

Zhe Han1,2, Juan Chen2, Min Chen2, Chen Zhang2, and Lizhi Xie3

1Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China, People's Republic of, 2Department of Radiology, Beijing Hospital, Beijing, China, People's Republic of, 3GE Healthcare, MR Research China, Beijing, China, People's Republic of

In this study we compared the association of intravoxel incoherent motion (IVIM) derived parameters with the histologic grade, N-stage, EGFR expression and K-RAS gene mutation of primary rectal cancer. Significant correlations were found between D values and differentiation grade, D* values and N-stage, f values and N-stage. IVIM derived parameters may be a promising imaging biomarker of tumor aggressiveness and prognosis.

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