Abstract #1970

Liver metastasis from colorectal cancer; a comparison of reproducibility of ADC between multiple sites and vendors, at 1.5 T and 3 T

Ryan Pathak¹, Neil A Thacker², David M Morris², Philippe Garteiser³, Sabrina Doblas³, Bernard E. Van Beers³, Houshang Amiri⁴, Arend Heerschap⁴, and Alan Jackson¹

¹The Wolfson Molecular Imaging Centre, University of Manchester, Manchester, United Kingdom, ²Centre for Imaging Sciences, University of Manchester, Manchester, United Kingdom, ³Laboratory of imaging biomarkers, INSERM, Paris Diderot University, Paris, France, ⁴Radboud University Medical Center, Nijmegen, Netherlands

ADC, calculated from diffusion-weighted MRI, is a potential quantitative imaging biomarker for detection of early treatment response. Imaging in the liver suffers from poor reproducibility, mainly as a result of respiratory motion. In this study we compare reproducibility in a multi-site, multi vendor setting at both 1.5 T and 3 T field strengths, for patients histologically diagnosed with colorectal cancer, who have radiological evidence of liver metastasis.

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