Abstract #1984

Age-related changes of white matter diffusion anisotropy measures in old age observed with Double Diffusion Encoding

Marco Lawrenz¹ and Juergen Finsterbusch¹

¹Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

With the help of double diffusion encoding experiments with two weighting periods applied successively microscopic tissue parameter can be gained. Rotationally invariant measures of the microscopic diffusion anisotropy such as the MA index may yield additional information complementary to DTI. Recent studies showed that MA can be determined in the living human brain, and normal values and their variation in groups of young and old healthy volunteers have been reported. In this study, the age-correlation of the diffusion anisotropy measures in terms of MA and FA values in a group of old volunteers (> 60 y) is discussed.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.