Abstract #1985

Utility of histogram analysis of apparent diffusion coefficient value for distinguishing pituitary atypical adenomas from typical adenomas

Mariko Doai¹, Naoko Tsuchiya¹, Hisao Tonami¹, and Osamu Tachibana²

¹Radiology, Kanazawa Medical University, Kahoku, Japan, ²Neurosurgery, Kanazawa Medical University, Kahoku, Japan

The purpose of this study is to evaluate the utility of histogram analysis of apparent diffusion coefficient (ADC) value for distinguishing pituitary atypical adenomas from typical adenomas. The ADC maps were reviewed using Ziostation2, and placed a 3D volume-of interest on the tumor. The entire tumor were computed. Histogram parameters were then compared between atypical adenomas (n=3) and typical adenomas (n=11). Skewness and kurtosis of ADC histogram were significantly lower for atypical adenoma as compared with typical adenoma. ADC histogram analysis on the basis of the entire tumor volume can be useful in distinguishing atypical adenomas from typical adenomas.

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