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Abstract #2026

Use envelope bounding to improve the stability of intravoxel incoherent motion modeling

Cheng-Ping Chien1, Feng Mao Chiu2, and Queenie Chan3

1Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, 2Philips Healthcare, Taipei, Taiwan, 3Philips Healthcare, Hong Kong, China, People's Republic of

Intravoxel incoherent motion (IVIM) model is useful tool to observe the microcirculatory perfusion, but its stability still needs to be improved. We propose the envelope bounding technique to reduce the fluctuated signal at low b-value, and use this new signal profile to fit IVIM model. This improvement gives a more stable outcome with fast diffusion (D*) and perfusion fraction (PF).

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