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Abstract #2029

Time dependence of diffusion and kurtosis parameters in the rat spinal cord

Sune Nørhøj Jespersen1,2, Brian Hansen1, Daniel Nunes3, and Noam Shemesh3

1CFIN, Aarhus University, Aarhus, Denmark, 2Dep. Physics and Astronomy, Aarhus University, Aarhus, Denmark, 3Champalimaud Neuroscience Programme, Champalimaud Centre for the Unknown, Lisbon, Portugal

Non-vanishing diffusion kurtosis and time-dependent diffusion are both hallmarks of nongaussian diffusion in biological tissues. Here we combine measurements of time-dependent DTI parameters and time dependence of mean kurtosis using fast kurtosis imaging in rat spinal cord. We observe substantial time dependence of all parameters in both white and gray matter.

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