Abstract #2039

Application of a combined IVIM-DTI model in ECG-triggered imaging of the human kidney

Fabian Hilbert¹, Simon Veldhoen¹, Tobias Wech¹, Henning Neubauer¹, Thorsten Alexander Bley¹, and Herbert Köstler¹

¹Department of Diagnostic and Interventional Radiology, University of Würzburg, Würzburg, Germany

Diffusion tensor imaging (DTI) accounts for anisotropy of diffusion, while the intravoxel incoherent motion (IVIM) model considers a fast moving pseudo-diffusion compartment. In the kidney DTI and IVIM parameters vary significantly depending on the time they are acquired within the cardiac cycle. A combined IVIM-DTI model incorporates anisotropic diffusion and anisotropic pseudo-diffusion parameters. The purpose of this study was to investigate the impact of the cardiac cycle on the combined IVIM-DTI model. While in DTI the fractional anisotropy of the diffusion tensor (FA_D) varies within the cardiac cycle, FA_D does not change in the IVIM-DTI model.

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