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Abstract #2039

Application of a combined IVIM-DTI model in ECG-triggered imaging of the human kidney

Fabian Hilbert1, Simon Veldhoen1, Tobias Wech1, Henning Neubauer1, Thorsten Alexander Bley1, and Herbert Köstler1

1Department of Diagnostic and Interventional Radiology, University of Würzburg, Würzburg, Germany

Diffusion tensor imaging (DTI) accounts for anisotropy of diffusion, while the intravoxel incoherent motion (IVIM) model considers a fast moving pseudo-diffusion compartment. In the kidney DTI and IVIM parameters vary significantly depending on the time they are acquired within the cardiac cycle. A combined IVIM-DTI model incorporates anisotropic diffusion and anisotropic pseudo-diffusion parameters. The purpose of this study was to investigate the impact of the cardiac cycle on the combined IVIM-DTI model. While in DTI the fractional anisotropy of the diffusion tensor (FAD) varies within the cardiac cycle, FAD does not change in the IVIM-DTI model.

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