Abstract #2043

Can Cramer-Ráo Lower Bound be used to find optimal b-values for IVIM?

Oscar Gustafsson^1,2, Maria Ljungberg^1,2, and Göran Starck^1,2

¹Department of Radiation Physics, Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, ²Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden

Cramer-Ráo Lower Bound is commonly used in experiment design optimization. Here we use it to find optimal b-value schemes for IVIM imaging. The optimization was generalized with regard to averaging and the characteristics of the results, given the input and the constraints, were studied. The resulting schemes never included more than the minimum number of four unique b-values, even though multiple sets of tissue parameters were included in the optimization. The optimized b-value schemes were compared to a typical one using simulations.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.