Abstract #2061

Is voxel-based apparent diffusion coefficient reproducible?

Masamitsu Hatakenaka¹, Koichi Onodera¹, Naomi Koyama¹, and Mitsuhiro Nakanishi²

¹Diagnostic Radiology, Sapporo Medical University, Sapporo, Japan, ²Division of Radiology, Sapporo Medical University Hospital, Sapporo, Japan

To evaluate reproducibility of voxel-based ADC, voxel-based ADC of the phantom was measured using clinical 3T MRI system. The direction of motion probing gradient affected the voxel-based ADC significantly in both echo planar imaging and turbo spin echo diffusion-weighted imaging. Also voxel-based ADC differed both between identical positioning examinations and between slightly different positioning examinations. Voxel-based ADC could not be reproduced sufficiently even in a phantom study. It would be recommended to pay enough attention when performing voxel-based ADC study like histogram analysis for tumor ADC.

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