Rodrigo de Luis-Garcia1, Angel Luis Guerrero2, Miguel Angel Tola-Arribas3, and Santiago Aja-Fernandez1
1Universidad de Valladolid, Valladolid, Spain, 2Hospital Clinico Universitario, Valladolid, Spain, 3Hospital Universitario Rio Hortega, Valladolid, Spain
Track-Density Imaging (TDI) can provide super resolution
images of the white matter of the brain. As it is based on the results of a
whole brain tractography process, it comprises information from different
features of the white matter diffusion. We exploit this information by
proposing a local analysis approach for TDI, and test it on two different
datasets where conventional TBSS analysis using FA did not yield any
significant differences. Results revealed the proposed method to be extremely
sensitive in the detection of white matter abnormalities, making it a promising
tool for white matter group studies.
