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Abstract #2123

T2-Mapping as a Predictor for Non-Perfused Volume in MRgFUS Treatments of Desmoid Tumors

Eugene Ozhinsky1, Matthew D. Bucknor1, and Viola Rieke1

1Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States

Desmoid tumors are benign but locally aggressive soft tissue tumors that arise from fibroblast cells. Focused ultrasound has shown promising results in reduction of tumor volume without significant side effects. Post-treatment contrast enhanced MR imaging allows assessment of the non-perfused volume (NPV), the gold standard assessment of the quantity of tumor ablation. However, safety concerns regarding heating of tissue after gadolinium injection prevent further treatment following the NPV assessment. We have shown that T2 mapping can be used to visualize the extent of ablation with focused ultrasound and be used as a predictor of NPV without the need for contrast injections.

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