Abstract #2246

T2 and T1rho values of grade 1 early degenerative cartilage in the distal femur using angle/layer dependent approach

Yasuhito Kaneko^1,2, Taiki Nozaki^1,3, Hon Yu^1,4, Kayleigh Kaneshiro¹, Ran Schwarzkopf⁵, and Hiroshi Yoshioka¹

¹Radiological Sciences, University of California, Irvine, Orange, CA, United States, ²Orthopaedic Surgery, Saitama City Hospital, Saitama, Japan, ³Radiology, St. Luke's International Hospital, Tokyo, Japan, ⁴John Tu and Thomas Yuen Center for Functional Onco-Imaging, University of California, Irvine, Orange, CA, United States, ⁵Orthopaedic Surgery, University of California, Irvine, Orange, CA, United States

We assessed patterns of T2 and T1rho value change with Outerbridge grade 1 lesions in OA patients compared to healthy control cartilage utilizing angle and layer dependent approach. T1rho values were more sensitive than T2 values to detect early cartilage degeneration with higher values in OA cartilage than in healthy control. However, T2 and T1rho values in grade 1 cartilage degeneration with signal heterogeneity can be lower compared to those in healthy cartilage.

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