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Abstract #2256

Statistical Comparison of Commonly Used Kinetic Models for Dynamic Contrast Enhanced Magnetic Resonance Imaging of Rheumatoid Arthritis in the Wrist

Sameer Khanna1,2, Nicolas Pannetier1, Jing Liu1, and Xiaojuan Li1

1Radiology, University of California, San Francisco, San Francisco, CA, United States, 2University of California, Berkeley, Berkeley, CA, United States

There has been a lack of statistical analysis to determine which kinetic model is best suited for analysis of the wrist. This study aims to rectify this by comparing the most commonly used models: Modified Tofts (MT), Two Compartment Uptake (2CU), and Two Compartment Exchange (2CX). Goodness of fit is analyzed by reduced chi squared, while statistical signifance between models is determined by wilcoxon signed-rank.

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