Abstract #2268

NEW MR PARAMETERS TO ASSESS AND MONITOR TENDON XANTHOMAS

James F Griffith¹, Teresa M Hu², David KW Yeung¹, D F Wang¹, Fan Xiao¹, and Brian Tomlinson²

¹Imaging and Interventional Radiology, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong, ²Medicine, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong

Achilles tendon xanthoma is a key clinical indicator of familial hypercholesteraemia (FH) and associated cardiovascular disease. Treatment that reduces the size of tendon xanthoma also benefits the arterial manifestations of FH. Ultrasound and MRI are often used to detect and monitor treatment response of tendon xanthomas using parameters such as tendon thickness, width and cross-sectional area. However, MR-based parameters derived from the DIXON technique to determine tendon volume and intratendinous percentage fat fraction may be more sensitive than traditional US and conventional MRI.

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