Abstract #2298

Bone marrow perfusion study on different BMD groups in elderly female

Chaoyang Zhang¹, Hu Xianghui², Heather T. Ma², Li Liang², and Chenfei Ye²

¹Harbin Institute of Technology Shenzhen Graduate School, Shenzhen, China, People's Republic of, ²Shenzhen, China, People's Republic of

This study utilized dynamic contrast enhanced (DCE) MRI and blood oxygen level dependent (BOLD) MRI as imaging method, using half quantitative analysis of two kinds of methods to study the relationship between the marrow blood perfusion, oxygen metabolism and bone mineral density. The research found that significant differences were observed in A, MaxEn and Halflife parameters among different BMD groups (p<0.05).In conclusion, different BMD groups has significant difference in perfusion ability on marrow. There is a link between the bone mineral density and marrow blood circulation and metabolism of oxygen. The changed blood circulation may be one of the reasons induced osteoporosis.

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