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Abstract #2297

Articular Cartilage Assessment Using T1ρ Mapping in Early Osteoarthritis Patients with Knee joint Pain

Jin Qu1, Xinwei Lei1, Ying ZHAN1, Huixia Li1, and Yu Zhang2

1Tianjin First Center Hospital, Tianjin, China, People's Republic of, 2Philips Healthcare, Beijin, China, People's Republic of

The purpose of this study was to evaluate articular cartilage degeneration in healthy subjects and patients with knee joint-pain as the only clinical manifestation using T1ρ measurements and to examine the interrelationship between cartilage abnormalities. Quantitative assessment of cartilage was performed using T1ρ mapping technique in 5 healthy volunteers and 17 knee joint-pain patients. T1ρ values were significantly elevated among patients with knee joint-pain compared to normal controls. Proteoglycan reduced in patients with knee joint-pain as the only clinical manifestation. Comparing to routine MR, T1ρ mapping could be more useful for these patients

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