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Abstract #2296

Quantification of Magnetization Transfer parameters in across different muscle groups

Chun Kit Wong1, Jamie X. M. Ho1, and Mary Stephenson1,2

1A*STAR-NUS Clinical Imaging Research Centre, Singapore, Singapore, 2Department of Medicine, National University of Singapore, Singapore, Singapore

Quantitative magnetization transfer (qMT) parameters can potentially be used as biomarker of diseases. In this study, qMT parameters’ nominal value are determined for selected muscle groups in healthy human subjects’ forearm, mid-thigh, and calf. Nominal values of qMT parameters are determined by taking the mean value across the subjects for each muscle group. From the results, strong correlations of qMT parameters between certain muscle groups within the same individual subjects are observed, suggesting that the qMT parameters' variation is biological in origin.

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