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Abstract #2326


Ina Vernikouskaya1,2, Alexander Pochert3, Mika Lindén3, and Volker Rasche1,2

1Internal Medicine II, University Hospital of Ulm, Ulm, Germany, 2Small Animal MRI, University of Ulm, Ulm, Germany, 3Inorganic Chemistry II, University of Ulm, Ulm, Germany

Quantification of 1H MR contrast agents (CA) is limited by the only indirect visualization of the changes of the relaxation properties of the surrounding tissue. Using alternative nuclei such as fluorine (19F) as CA enables direct and quantifiable readout of local CA aggregations, since the 19F signal linearly correlates with its local concentration. However non-uniformity of the transmit/receive radiofrequency fields impact the resulting absolute signal, leading to wrong quantification results. Application of an easy-to-use time-efficient B1+/B1--mapping technique for correction of the 19F signal in vivo is presented in this work.

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