Abstract #2349

Investigating Spectral Selectivity of the bSSFP Sequence for High Resolution 3D Dynamic Hyperpolarized 13C MRI at 3T Using C2-Pyruvate and Urea

Eugene Milshteyn¹, Cornelius von Morze¹, Hong Shang¹, Galen D Reed², and Daniel B Vigneron¹

¹Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States, ²HeartVista, Menlo Park, CA, United States

Hyperpolarized ¹³C MR imaging can provide simultaneous assessments of metabolism and perfusion to study disease processes. High resolution dynamic imaging is needed to fully understand these processes, but is challenging, especially on clinically relevant systems. This project investigated new methods for spectral selectivity with SNR-efficient bSSFP sequences to provide improved high resolution 3D dynamic in vivo HP ¹³C MR imaging at 3T.

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