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Abstract #2349

Investigating Spectral Selectivity of the bSSFP Sequence for High Resolution 3D Dynamic Hyperpolarized 13C MRI at 3T Using C2-Pyruvate and Urea

Eugene Milshteyn1, Cornelius von Morze1, Hong Shang1, Galen D Reed2, and Daniel B Vigneron1

1Radiology and Biomedical Imaging, UCSF, San Francisco, CA, United States, 2HeartVista, Menlo Park, CA, United States

Hyperpolarized 13C MR imaging can provide simultaneous assessments of metabolism and perfusion to study disease processes. High resolution dynamic imaging is needed to fully understand these processes, but is challenging, especially on clinically relevant systems. This project investigated new methods for spectral selectivity with SNR-efficient bSSFP sequences to provide improved high resolution 3D dynamic in vivo HP 13C MR imaging at 3T.

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