Abstract #2353

Rapid, High-Resolution 3D 1H-MRSI of the Brain based on FID Acquisitions

Mohammed Azeem Sheikh¹, Fan Lam², Chao Ma², Bryan Clifford³, and Zhi-Pei Liang³

¹Physics, University of Illinois at Urbana-Champaign, Urbana, IL, United States, ²Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL, United States, ³Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States

In 1H-MRSI, data is typically acquired with spin echo sequences with relatively long acquisition delay, often motivated by the need for water, lipid, and baseline suppression. Here, we present a new method to obtain high-resolution 1H-MRSI data with an FID-based acquisition that has a very short acquisition delay, enabled by a new scheme for nuisance signal removal. The new acquisition method enables short repetition time and rapid acquisition of spectroscopic data. Experimental results demonstrate in vivo 3D 1H-MRSI of the brain with isotropic 3 mm resolution in 15 minutes.

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