Meeting Banner
Abstract #2380

Enhancement of signal intensity using a wireless coil for FT-EPR oximetry study

Ayano Enomoto1, Gadisetti V. R. Chandramouli2, Alan P Koretsky3, Chunqi Qian4, Murali K Cherukuri1, and Nallathamby Devasahayam1

1Radiation Biology Branch, National Cancer Institute, Bethesda, MD, United States, 2GenEpria Consulting Inc., Columbia, MD, United States, 3National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States, 4Department of Radiology, Michigan State university, East Lansing, MI, United States

Sensitivity enhancement is required to detect the weak signals with Fourier transform Electron Paramagnetic Resonance (FT-EPR). In the proposed method, a small amount of sample was placed at a distance less than half the diameter of the receiving surface coil. The signal was enhanced by a wirelessly pumped coil. Presently, we used the TCNQ for our studies to study signal enhancement. Here, we achieved 7-fold of improvement in signal intensity in compared with conventional FT-EPR acquisition. We will show the results of in vivo oximetry using oxygen sensing solids LiPc and LiNc in in vivo applications to measure tissue oxygenation.

This abstract and the presentation materials are available to members only; a login is required.

Join Here