Abstract #2411

Proton MR Metabolic Profiling in combination with serum procalcitonin levels as rapid indicators for differentiation of Urosepsis

Suruchi Singh¹, Tanushri Chatterji², Manodeep Sen², Ishwar Ram³, and Raja Roy¹

¹Centre of Biomedical Research, Lucknow, India, ²Department of Microbiology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India, ³Department of Urology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India

This study is a new approach for the diagnosis of Urosepsis using Proton MR spectroscopy along with serum procalcitonin levels. The study insights, NMR based metabolic profiling for differentiation of Urosepsis, a medical emergency which requires immediate patient care. The analysis takes less than one hour for disease identification, thus enabling quick and efficient patient management. The Principal Component Analysis (PCA) displayed that glucose and lactate in serum were the major confounders in differentiating Urosepsis cases from Healthy controls. The training set of Partial least square Discriminant analysis (PLS-DA) provided precise prediction of the test set in serum samples.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.