Abstract #2427

Application of High B-Value High-Resolution Diffusion-Weighted Imaging in Differentiating Malignant from Benign Thyroid Nodules

Qingjun Wang¹, Yong Guo¹, Jing Zhang¹, Minghua Huang¹, Qinglei Shi², and Tianyi Qian²

¹Radiology, Chinese Navy General Hospital, Beijing, China, People's Republic of, ²Scientific Marketing, Siemens Healthcare, Beijing, China, People's Republic of

In this study, we evaluated the advantages of using high b-value high-resolution diffusion-weighted MR imaging (DWI) to differentiate between malignant and benign thyroid nodules. This prospective study included 28 consecutive patients with thyroid nodules (14 malignant nodules in 10 patients and 24 benign nodules in 20 patients). Three b-values including b-values of 0, 800 and 2000 sec/mm² and a Readout Segmentation Of Long Variable Echo-trains (RESOLVE) imaging technique were used in the high b-value high-resolution DWI. The results showed that the high b-value high-resolution DWI can further increase the diagnostic accuracy for thyroid nodules with the best sensitivity, specificity and area under receiver operating characteristic curve (AUC) than low b-value or single high b-value.

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