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Abstract #2441

Quantification of transverse relaxation time changes in rectal tissue during fixation at ultra-high field MRI

Quincy van Houtum1, Dennis D.W.J. Klomp1, and Marielle M.E.P. Philippens1

1Imaging, UMC Utrecht, Utrecht, Netherlands

In this study we investigate the transverse relaxation effects at 7T during the fixation process in rectal specimens as a preparation for 7T MRI validation of rectal tumor regression with pathology. T2 and T2* were measured every 2 hours during fixation process in six different pig recta. Images allowed mapping of relaxation time at high spatial resolution. The circular muscle showed a decrease of 25% in T2* whilst other tissues remained constant over time for both parameters. A T2* decrease of 25% is seen in the circular muscle of the rectal wall was noticed whilst other tissue-regions remained constant. High resolution and SNR allowed for anatomical delineation and measuring the change of transverse relaxation times.

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