Abstract #2442

MRI biomarkers for pancreatic ductal adenocarcinoma

Navid Farr¹, Paolo Provenzano², Joshua Park³, Sunil Hingorani², and Donghoon Lee³

¹Department of Bioengineering, University of Washington, Seattle, WA, United States, ²Fred Hutchinson Cancer Research Center, Seattle, WA, United States, ³Department of Radiology, University of Washington, Seattle, WA, United States

Pancreatic cancer is a devastating disease with poor prognosis. Pancreatic tumor therapy has been ineffective in part because pancreatic tumors have a dense stroma inhibiting penetration of chemotherapeutic drugs into the tumor. We performed multi-parametric MRI at high resolution to noninvasively assess tumor progression and responses to effective treatment. We used T1 and T2 relaxation, diffusion, magnetization transfer effects along with 3 dimensional volume measurements to characterize the tumors. MR measurements were then compared with histopathological results.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.