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Abstract #2452

Multivariate assessment of brain glioma using hybrid IVIM and DK MRI

Ya-Fang Chen1, Hsiang-Kuang​ Liang2, and Wen-Chau Wu3,4

1Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan, 2Radiation Oncology, National Taiwan University Hospital, Taipei, Taiwan, 3Graduate Institute of Oncology, National Taiwan University, Taipei, Taiwan, 4Clinical Medicine, National Taiwan University, Taipei, Taiwan

In the present study, we investigated the feasibility of hybrid intravoxel incoherent motion and diffusion kurtosis MR imaging in assessing brain gliomas. Our data showed that combined intravascular fraction (a surrogate measure of cerebral blood volume), diffusion coefficient (a measure of diffusivity), and diffusion kurtosis coefficient (a measure of diffusion heterogeneity) may better demarcate brain gliomas through exploration of multiple pathophysiological aspects.

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